In 2012, MS has been considered mainly an inflammatory disorder, recent evidence, however, revealed the importance of neurodegenerative events, opening the possibility to cannabinoid treatment. Mice were used

BACKGROUND: Treatment with WIN55,512-2, a potent CB₁ and CB₂agonist, was reported to be effective to ameliorate tremor and spasticity in mice with chronic relapsing experimental autoimmune encephalomyelitis,

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