In 2009, Cannabinoid CB₂ receptor agonists protect the striatum against malonate toxicity: relevance for Huntington’s disease

BACKGROUND: Examined this hypothesis in a rat model of Huntington’s disease (HD) generated by intrastriatal injection of the mitochondrial complex II inhibitor malonate.

You can read the full article here => https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706932/