In 2003, Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection: A Randomized, Placebo-Controlled Clinical Trial

BACKGROUND: Cannabinoid use could potentially alter HIV RNA levels by two mechanisms: immune modulation or cannabinoid–protease inhibitor interactions (because both share cytochrome P-450 metabolic pathways)

You can read the full article here => https://www.researchgate.net/publication/10574358_Short-Term_Effects_of_Cannabinoids_in_Patients_with_HIV-1_Infection_A_Randomized_Placebo-Controlled_Clinical_Trial