Alzheimer’s Research-2017 Nov

In 2017, Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target BACKGROUND: review the role of eCB system in two chronic neurodegenerative diseases, in which the neuroprotective effects following CB receptors modulation have been reported in different studies. Specifically, we will focus on the role of CB2 receptors and their agonists, as …

Alzheimer’s Research-2004 Feb

In 2004, Neuroprotective effect of cannabidiol, a non‐psychoactive component from Cannabis sativa, on β‐amyloid‐induced toxicity in PC12 cells BACKGROUND: The aim of the present study is to evaluate the possible neuroprotective effect of cannabidiol on β‐amyloid‐induced neurotoxicity. For this purpose we evaluated the effect of cannabidiol on cell viability, reactive oxygen species (ROS) formation and membrane lipoperoxidation, …

Autism Research-2011 Mar

In 2011, Consequences of Cannabinoid and Monoaminergic System Disruption in a Mouse Model of Autism Spectrum Disorders BACKGROUND: Goal of this study, was to use the mouse model to determine the role if any of the endocannabinoid system in autism. This was accomplished using the BTBR T+tf/J mice with autism-like behavioral phenotypes. The behavioral, morphological and …

Autism Research-2017 Oct

In 2017, Treating Autism With Cannabis Now Has Scientific Support. To understand how CBD was treating autistic-like behavior in our mice, we recorded the electrical signals in individual brain cells BACKGROUND: While clinical trials showed that CBD was an effective anti-epileptic in patients, they never investigated CBD’s effects on ASD. In fact, no clinical study has ever looked …

Cannabis in Autism Treatment-2016 May

in 2016, Leafly How Does Cannabis Consumption Affect Autism? BACKGROUND: In the absence of empirical data, however, is a growing body of anecdotal evidence that cannabis is making children with autism happier and healthier. And some doctors are listening. You can read the full article here => https://www.leafly.com/news/health/how-does-cannabis-consumption-affect-autism

Cannabis and Asthma Findings-2015 Sep

In 2015, Does Cannabis Treat Asthma? BACKGROUND: THC is a bronchial dilator, making it an effective treatment for asthma and related respiratory conditions due to its anti-inflammatory properties. CBD decreases inflammation and may cause a reduction in mucus hyper-secretion, a major symptom of asthma. You can read the full article here => https://www.massroots.com/learn/does-cannabis-treat-asthma?is=1

Osteoarthritis Research-2013 Nov

In 2013, Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint BACKGROUND: The aim of this study was to determine whether activation of the CB2 receptor attenuates pain behaviour in the MIA model of OA pain, and then to investigate the sites of action, and mechanisms by which, analgesic effects were …

Cannabis & Osteoarthritis-2016 Feb

In 2016, Cannabis for the Treatment of Osteoarthritis BACKGROUND: Cannabis has been proven, through both research studies and anecdotal evidence, to relieve the symptoms and sometimes core diseases that plague literally billions of people worldwide. One of the diseases for which is has very targeted efficacy is arthritis. There are two general categories of arthritis: Osteo and rheumatoid. You …

Arthritis Research-2000 June

In 2000, The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis BACKGROUND: The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis, was explored in murine collagen-induced arthritis (CIA). CBD treatment commenced at the first clinical signs of arthritis You can read the full article here => http://www.pnas.org/content/97/17/9561.full