In 2011, Consequences of Cannabinoid and Monoaminergic System Disruption in a Mouse Model of Autism Spectrum Disorders

BACKGROUND: Goal of this study, was to use the mouse model to determine the role if any of the endocannabinoid system in autism. This was accomplished using the BTBR T+tf/J mice with autism-like behavioral phenotypes. The behavioral, morphological and neurochemical alterations in this model will allow us to test our hypothesis about the causes of autism, and may serve as an index for the evaluation of proposed treatment strategies in combination with other transgenic models.

You can read the full article here => https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137184/